The resort is located at 777 Casino Drive, in Cherokee, NC, and is open 24 hours each day. Harrah’s Cherokee Casino Resort is owned by the Eastern Band of Cherokee Indians, but it is operated by Caesars Entertainment. Spend a weekend there and experience the fun and luxury for yourself. It was North Carolina’s first casino and has grown into the fabulous hotel resort it is today. Nestled in the mountains of Western North Carolina, Harrah’s Cherokee Casino Resort is like visiting Las Vegas without having to travel too far.